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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS7
All Species:
24.85
Human Site:
T226
Identified Species:
42.05
UniProt:
P49802
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49802
NP_002915.3
495
57668
T226
R
M
R
N
P
H
K
T
R
K
S
V
Y
G
L
Chimpanzee
Pan troglodytes
XP_001159739
487
56751
T226
R
M
R
N
P
H
K
T
R
K
S
V
Y
G
L
Rhesus Macaque
Macaca mulatta
XP_001095075
499
57951
L230
P
H
K
T
E
G
K
L
T
S
S
V
Y
G
L
Dog
Lupus familis
XP_537503
683
78241
V216
R
L
K
N
P
Q
K
V
K
K
S
V
Y
G
V
Cat
Felis silvestris
Mouse
Mus musculus
O54829
469
54704
T226
R
M
R
N
P
H
K
T
R
K
S
V
Y
G
L
Rat
Rattus norvegicus
P49803
477
55673
T226
R
M
R
N
P
H
K
T
R
K
S
V
Y
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514330
608
70692
T226
R
M
K
N
P
H
K
T
R
K
S
V
Y
G
L
Chicken
Gallus gallus
XP_419551
506
58927
T226
R
M
R
N
P
H
K
T
R
K
S
V
Y
G
L
Frog
Xenopus laevis
NP_001079945
471
54554
V228
R
M
K
N
P
Q
K
V
K
K
S
V
Y
G
V
Zebra Danio
Brachydanio rerio
NP_001002541
459
53605
G205
D
V
H
R
P
V
P
G
C
V
N
T
T
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523380
647
70137
T403
M
P
G
C
V
N
T
T
E
I
D
I
K
K
A
Honey Bee
Apis mellifera
XP_393403
510
59946
P269
K
A
C
R
T
Y
K
P
F
P
K
L
S
K
H
Nematode Worm
Caenorhab. elegans
P49809
555
63260
S226
R
S
G
R
P
K
Y
S
S
G
G
H
A
A
L
Sea Urchin
Strong. purpuratus
XP_782272
467
54702
R217
M
D
I
K
K
L
S
R
I
N
R
T
F
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
98.8
51
N.A.
91.3
95.1
N.A.
76.8
87.7
70.3
83
N.A.
41.2
53.5
34.5
56.1
Protein Similarity:
100
96.7
98.8
61.9
N.A.
93.7
96.1
N.A.
79.2
91.9
81.8
87.8
N.A.
53.7
71.9
51.1
71.9
P-Site Identity:
100
100
40
60
N.A.
100
100
N.A.
93.3
100
66.6
6.6
N.A.
6.6
6.6
20
0
P-Site Similarity:
100
100
46.6
86.6
N.A.
100
100
N.A.
100
100
86.6
26.6
N.A.
20
26.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
0
15
0
0
8
0
8
0
8
8
0
0
65
0
% G
% His:
0
8
8
0
0
43
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
0
8
0
0
0
% I
% Lys:
8
0
29
8
8
8
72
0
15
58
8
0
8
22
8
% K
% Leu:
0
8
0
0
0
8
0
8
0
0
0
8
0
0
58
% L
% Met:
15
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
58
0
8
0
0
0
8
8
0
0
0
0
% N
% Pro:
8
8
0
0
72
0
8
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
65
0
36
22
0
0
0
8
43
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
8
8
8
65
0
8
0
0
% S
% Thr:
0
0
0
8
8
0
8
50
8
0
0
15
8
0
0
% T
% Val:
0
8
0
0
8
8
0
15
0
8
0
65
0
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
65
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _